Retatrutide — an investigational peptide being studied mainly for weight loss and metabolic health. It’s not FDA-approved yet, but it’s gotten a lot of attention because of strong trial results.
Retatrutide is a once-weekly injectable peptide that activates 3 receptors:
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GLP-1 → lowers appetite, slows stomach emptying
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GIP → may improve insulin response and help with weight regulation
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Glucagon receptor → may increase energy expenditure/fat burning